Improved characterization of medically relevant fungi in the human respiratory tract using next-generation sequencing

Table 1 Groups of subjects appearing in this study

Group	Subjects (n)	Description	Median CD4 count	Bronchoscopy procedure	Reference
1A	8	HIV+ off ART, CD4 > 400	769	Two scope	This study
1B	3	HIV+ off ART, CD4 < 400	315	Two scope	This study
2B	8	HIV+ on ART, no lung disease	674	Two scope	This study
3B	6	HIV-, no lung disease		Two scope	16S data [20], ITS data [21]
3C	4	HIV-, no lung disease		None	This study
3D	6^a	HIV-, no lung disease		Single scope	This study
Pulm	13	HIV-, mixed lung disease		Single scope	This study
Transplant	42	Lung transplant recipients		Single scope	Time points with paired BAL and OW samples [21]^b

^aFour subjects in group 3D were also sampled in group 3B. In each case, the group 3D sample was taken more than 1 year after the 3B sample (see Additional file 1 for details).
^bSample sets Tx34B and Tx41B appear as Tx34 and Tx41, respectively, in Charlson 2012. The initial time points were not included in the previous publication because OW samples were not collected at the time of sampling.

ISSN: 1474-760X