Figure 12
From: Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data
Mutation multiplicities compared to subclonal CNs. Sample 5 VAF fits to array CN data of type A segments and their mutations for the two most plausible positions of (1,1): g3 = 1 or g6 = 1. Each scenario results in different minor (green) and major (blue) subclone A integer CN estimates, and multiplicities of the mutations if these sit on A cells only (red). Light and black horizontal lines show expected y-levels of clonal mutations and mutations present on only non-A cells, all according to assumptions 3 to 6. For details, see text.