Figure 7From: A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulatorsExpression pattern divergence between paralogs correlated with promoter divergence. This figure consists of six parts identified as ( a ) - ( f ). Expression pattern divergence between duplicates was measured with either ( a ) Pearson’s correlation; ( b ) the Kendall rank correlation coefficient; or ( c ) Spearman's rank correlation coefficient. Promoter divergence was measured using Jaccard index (JI). The correlation disappeared when duplicate pairs were randomized ( d-e-f ) proving that it was well defined and specific. The red line signified the linear model for the smoother line, while the blue line signified the non-linear model. This figure suggests that the correlation between the breadth of expression and the number of transcription factor binding sites persisted if alternative non-parametric measures of expression distances between paralogs were used. Details of the correlations were given in Table 8.Back to article page