Figure 3

ER, GATA3, FOXA1, and transcript 13741 are up-regulated in early neoplasia and cancer. Images of IHC for ER, GATA3, and FOXA1 for a matched set of normal breast, early neoplasia, and invasive ductal carcinoma (donor ID 22666) at 400×. (A) Hematoxylin and eosin (H&E) staining of normal tissue; (B) H&E of early neoplasia; (C) H&E of invasive ductal carcinoma; (D) ER in normal tissue; (E) ER in early neoplasia; (F) ER in invasive ductal carcinoma; (G) GATA3 in normal tissue; (H) GATA3 in early neoplasia; (I) GATA3 in invasive ductal carcinoma; (J) FOXA1 in normal tissue; (K) FOXA1 in early neoplasia; (L) FOXA1 in invasive ductal carcinoma (M-O) RNA in situ hybridization for transcript 13741 in normal tissue (M), early neoplasia (N), and invasive ductal carcinoma (O).