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Table 2 Kinetic parameters of the resistant (119 F) and susceptible (L119) GSTe2 alleles

From: A single mutation in the GSTe2 gene allows tracking of metabolically based insecticide resistance in a major malaria vector

  Vmax(DDE μmol.min−1.mg−1) K m (μM DDT) Kcat (s−1) Kcat/K m (μM−1.s−1)
119 F-GSTe2 60.8 ± 7.2 149.6 ± 39.6 47312 ± 5297 316.3
L119-GSTe2 3.75 ± 0.26 34 ± 5.9 3129 ± 222.6 92.0
  1. Three independent assays were performed for both alleles and the results show mean ± standard deviation.