Synaptic function is altered in emr-1 mutants. (A) Fold increase in expression of selected genes involved in synaptic transmission in emr-1(RNAi) lem-2(tm1582) animals. Error bars indicate minimum and maximum values. (B) Aldicarb sensitivity experiments in wild type (WT), emr-1(gk119), lem-2(tm1582) and emr-1(gk119)/+ lem-2(tm1582) mutants. Synaptic function was evaluated based on paralysis induced by the cholinesterase inhibitor aldicarb. Data points show the mean of four experiments and error bars indicate standard error of the mean.