Skip to main content

Table 1 Mammalian evolutionarily conserved sites

From: Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

  chr Position Strand Gene Region ref_id:nucleotide cange:aa change
1 chr1 160302244 - COPA CDS NM_001098398:c.A490G:p.I164V
2 chr11 105804694 + GRIA4 CDS NM_000829:c.A2293G:p.R765G
3 chr11 105815132 + GRIA4 intron  
4 chr11 105816106 + GRIA4 intron  
5 chr11 105816129 + GRIA4 intron  
6 chr11 105816145 + GRIA4 intron  
7 chr11 105816160 + GRIA4 intron  
8 chr12 5021742 + KCNA1 CDS NM_000217:c.A1198G:p.I400V
9 chr13 46090371 + COG3 CDS NM_031431:c.A1903G:p.I635V
10 chr14 26917530 - NOVA1 CDS NM_006489:c.A1087G:p.S363G
11 chr14 101506074 + mir376C microRNA  
12 chr17 43045220 - C1QL1 CDS NM_006688:c.A197G:p.Q66R
13 chr19 47152854 - DACT3 CDS NM_145056:c.A775G:p.R259G
14 chr2 20450819 - PUM2 3′UTR  
15 chr2 21233202 - APOB CDS NM_000384:c.C6538G:p.Q2180stop
16 chr2 210835613 + UNC80 CDS NM_032504:c.A7990G:p.S2664G
17 chr20 36147533 - BLCAP CDS NM_001167821:c.A44G:p.K15R
18 chr20 36147563 - BLCAP CDS NM_001167821:c.A14G:p.Q5R
19 chr20 36147572 - BLCAP CDS NM_001167821:c.A5G:p.Y2C
20 chr20 36148080 - BLCAP intron  
21 chr20 52104918 + TSHZ2 3′UTR  
22 chr21 30953750 - GRIK1 CDS NM_175611:c.A1862G:p.Q621R
23 chr21 34922801 + SON CDS NM_032195:c.A1264G:p.T422A
24 chr21 34923319 + SON CDS NM_032195:c.A1782G:p.L594L
25 chr21 46595620 + ADARB1 intron  
26 chr3 53820892 + CACNA1D CDS NM_001128839:c.A4791G:p.I1597M
27 chr3 58141801 + FLNB CDS NM_001164319:c.A6815G:p.Q2272R
28 chr3 62423807 - CADPS CDS NM_183393:c.A3512G:p.E1171G
29 chr4 57976234 - IGFBP7 CDS NM_001253835:c.A284G:p.K95R
30 chr4 57976286 - IGFBP7 CDS NM_001253835:c.A232G:p.R78G
31 chr4 158257875 + GRIA2 CDS NM_000826:c.A1820G:p.Q607R
32 chr4 158257879 + GRIA2 CDS  
33 chr4 158258136 + GRIA2 intron  
34 chr4 158258137 + GRIA2 intron  
35 chr4 158281294 + GRIA2 CDS NM_000826:c.A2290G:p.R764G
36 chr5 156736808 + CYFIP2 CDS NM_001037332:c.A958G:p.K320E
37 chr6 34100903 - GRM4 CDS NM_000841:c.A371G:p.Q124R
38 chr6 44120349 + TMEM63B CDS NM_018426:c.A1856G:p.Q619R
39 chr6 102337689 + GRIK2 CDS NM_001166247:c.A1699G:p.I567V
40 chr6 102337702 + GRIK2 CDS NM_001166247:c.A1712G:p.Y571C
41 chr6 102372589 + GRIK2 CDS NM_001166247:c.A1862G:p.Q621R
42 chr6 102372630 + GRIK2 intron  
43 chr6 102374616 + GRIK2 intron  
44 chr6 102374643 + GRIK2 intron  
45 chr6 150093334 + PCMT1 intron  
46 chr8 103841636 - AZIN1 CDS NM_148174:c.A1099G:p.S367G
47 chr8 103841637 - AZIN1 CDS NM_148174:c.A1098G:p.E366E
48 chr9 97847739 + mir23B microRNA  
49 chrX 114082682 + HTR2C CDS NM_000868:c.A466G:p.I156V
50 chrX 114082684 + HTR2C CDS NM_000868:c.A468G:p.I156M
51 chrX 114082689 + HTR2C CDS NM_000868:c.A473G:p.N158S
52 chrX 114082694 + HTR2C CDS NM_000868:c.A478G:p.I160V
53 chrX 122598962 + GRIA3 CDS NM_000828:c.A2323G:p.R775G
54 chrX 122598998 + GRIA3 intron  
55 chrX 135111055 + SLC9A6 intron  
56 chrX 135111070 + SLC9A6 intron  
57 chrX 151358319 - GABRA3 CDS NM_000808:c.A1026G:p.I342M
58 chrX 153579737 - FLNA intron  
59 chrX 153579950 - FLNA CDS NM_001456:c.A6998G:p.Q2333R
  1. List of conserved editing sites. Coordinates are based on the genome version GRCh37/hg19. For each site, the table includes the following information: chromosome, genomic coordinate, strand, gene name, genomic compartment, RefSeq id (if available), editing transformation, and coordinate related to the Refseq ID, and amino acid change (for the same Refseq ID).