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Figure 1 | Genome Biology

Figure 1

From: The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

Figure 1

Most transcripts in wild-type and thunder CD8+T cells are fully spliced, yet a minority retain one or more introns. The genome-wide distribution of intron splicing frequency is skewed towards full removal (0% intron retention), but also includes fully unspliced transcripts (100% intron retention). The majority of introns (87%) have a splicing efficiency of greater than 90%, meaning they remain unspliced in fewer than 10% of polyadenylated mRNAs; 0.94% of introns have a splicing efficiency of less than 50% and were retained in more than 50% of polyadenylated mRNAs present in our RNA-seq data.

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Genome Biology

ISSN: 1474-760X

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