Figure 5

GraphProt sequence and structure motifs capture known binding preferences. We compare data from the literature (left) with visualized GraphProt sequence and structure motifs (right) and substantial agreement is evident, especially with known sequence specificities. Structure motifs are annotated with the full set of structure elements: stems (S), external regions (E), hairpins (H), internal loops (I), multiloops (M) and bulges (B). The character size correlates with the importance for RBP binding. For ELAVL1, we show the motif for ELAVL1 PAR-CLIP (C). PAR-CLIP, photoactivatable-ribonucleoside-enhanced cross-linking and immunoprecipitation; RBP, RNA-binding protein.