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Figure 3 | Genome Biology

Figure 3

From: Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells

Figure 3

5hmC was enriched at H3K27me3 loci in embryonic stem cells (ESCs) but not in differentiated cells. (A) Heatmaps of 5hmC and H3K27me3 of genomic regions around the TSS (± 5 kb) in ESCs, mouse embryonic fibroblasts (MEFs), brain, and liver, rank-ordered by mRNA expression level of each cell type. (B) Profile distribution of 5hmC and H3K27me3 at the TSS (± 5kb) in H3K27me3-positive genes.

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Genome Biology

ISSN: 1474-760X

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