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Table 1 Performance of the algorithms on simulated data with one tumor population (n = 2)

From: THetA: inferring intra-tumor heterogeneity from high-throughput DNA sequencing data

  % correct C Copy number error (median) Purity error (median)
k THetA ASCAT CNAnorm ABSOLUTE THetA ASCAT CNAnorm ABSOLUTE THetA ASCAT CNAnorm ABSOLUTE
3 100.0 85.0 40.0 70.0 0.0 0.0 0.103 0.000 0.004 0.040 0.068 0.010
4 90.0 55.0 8.3 50.0 0.0 0.0 0.163 0.013 0.004 0.037 0.064 0.010
5 85.0 50.0 6.7 15.0 0.0 0.013 0.185 0.160 0.004 0.062 0.038 0.075
6 55.0 40.0 0.0 15.0 0.0 0.026 0.291 0.433 0.006 0.063 0.066 0.157
7 30.0 15.0 0.0 10.0 0.031 0.036 0.445 0.471 0.005 0.069 0.108 0.149