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Table 2 Summary of the SVM classifications containing the means, standard deviations, and 95% confidence intervals (CI) of the accuracy (acc), specificity (spec), sensitivity (sens) running 100 repetitions of 10-fold cross-validations with linear kernel.

From: A blood based 12-miRNA signature of Alzheimer disease patients

Comparison Classification Permutation test
  Acc Spec Sens Acc Spec Sens
AD vs. control 93.3% ± 4.6
CI:92.4-94.2%
95.1% ± 5.4
CI:94.1-96.2%
91.5% ± 5.8
CI:90.4-92.7%
50.7% ± 12.5
CI:48.2-53.1%
50.7% ± 13.3
CI:48.1-53.3%
50.7% ± 14.1
CI:47.9-53.4%
MCI vs. control 84.2% ± 3.7
CI:83.4-84.9%
81.1% ± 5.6
CI:80.0-82.2%
87.7% ± 3.7
CI:87.0-88.5%
51.3% ± 11.4
CI:49.0-53.5%
52.0% ± 12.2
CI:50.0-54.4%
50.4% ± 13.5
CI:47.8-53.1%
PSY vs. control 97.1% ± 1.6
CI:96.8-97.4%
95.3% ± 1.7
CI:95.0-95.6%
99.0% ± 2.4
CI:98.5-99.4%
48.7% ± 10.6
CI:46.7-50.8%
48.5% ± 12.4
CI:46.0-50.9%
49.0% ± 12.1
CI:46.6-50.8%
Other ND vs. control 82.8% ± 5.0
CI:81.8-83.7%
84.0% ± 5.8
CI:83.0-85.2%
81.4% ± 6.7
CI:80.1-82.7%
50.3% ± 10.3
CI:48.3-52.3%
50.7% ± 11.7
CI:48.4-53.0%
50.0% ± 12.0
CI:47.6-52.3%
NEURO vs. control 86.1% ± 5.7
CI:85.0-87.2%
88.7% ± 6.8
CI:87.3-90.0%
83.6% ± 6.6
CI:82.3-84.9%
49.9% ± 10.8
CI:47.8-52.1%
50.1% ± 11.5
CI:47.9-52.3%
49.8% ± 13.3
CI:47.2-52.3%
AD vs. MCI 75.6% ± 7.8
CI:74.1-77.2%
76.7% ± 8.3
CI:75.1-78.4%
74.6% ± 9.7
CI:72.7-76.5%
50.6% ± 9.4
CI:48.7-52.4%
51.2% ± 10.4
CI:49.1-53.2%
49.9% ± 11.7
CI:47.7-52.2%
AD vs. PSY 77.8% ± 4.0
CI:77.0-78.5%
76.3% ± 4.8
CI:75.4-77.3%
79.2% ± 5.4
CI:78.1-80.2%
50.0% ± 8.0
CI:48.5-51.6%
49.1% ± 9.3
CI:47.3-50.9%
51.1% ± 10.3
CI:49.1-53.1
AD vs. other ND 73.8% ± 4.4
CI:72.9-74.7%
75.2% ± 4.7
CI:74.2-76.1%
72.4% ± 6.4
CI:71.2-73.7%
50.1% ± 7.3
CI:48.7-51.5%
49.2% ± 9.4
CI:47.4-51.1%
51.0% ± 8.5
CI:49.3-52.7%
  1. The right part of the table contains the results for the permuted class labels. PSY = psychological disorders (DEP, BD, SCHIZ), other ND = other neurodegenerative disorders (PD, MS, MCI), NEURO = PSY + other ND