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Table 3 Enrichment of LTR-driven vlincRNAs in malignant, immortalized, primary and embryonic stem cells.

From: VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer

Cell line/Tissue Cell Type Number of vlincRNAs VlincRNAs Assigned to LTR* promoters % Assigned to LTR promoters Overlap Expected by Chance Fold over chance p-value
K562 Malignant 407 119 29.23% 4.5 26.6 7.2E-130
HepG2 Malignant 501 71 14.17% 6.3 11.4 7.9E-51
GM12878 Immortalized 591 47 7.95% 3.5 13.5 7.1E-37
NHEK Primary 248 1 0.40% 1.1 0.9 0.67
HUVEC Primary 340 10 2.94% 1.0 10.0 9.4E-08
H1-hEsc Embryonic Stem 469 68 14.49% 3.5 19.6 5.4E-64
  1. *Defined as All promoters found in the respective cell line and overlapping an LTR