Table 3 Enrichment of LTR-driven vlincRNAs in malignant, immortalized, primary and embryonic stem cells.
From: VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer
Cell line/Tissue | Cell Type | Number of vlincRNAs | VlincRNAs Assigned to LTR* promoters | % Assigned to LTR promoters | Overlap Expected by Chance | Fold over chance | p-value |
|---|---|---|---|---|---|---|---|
K562 | Malignant | 407 | 119 | 29.23% | 4.5 | 26.6 | 7.2E-130 |
HepG2 | Malignant | 501 | 71 | 14.17% | 6.3 | 11.4 | 7.9E-51 |
GM12878 | Immortalized | 591 | 47 | 7.95% | 3.5 | 13.5 | 7.1E-37 |
NHEK | Primary | 248 | 1 | 0.40% | 1.1 | 0.9 | 0.67 |
HUVEC | Primary | 340 | 10 | 2.94% | 1.0 | 10.0 | 9.4E-08 |
H1-hEsc | Embryonic Stem | 469 | 68 | 14.49% | 3.5 | 19.6 | 5.4E-64 |