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Table 2 Distribution of LTRs in Active promoters in malignant, immortalized, primary and embryonic stem cells.

From: VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer

 

Cell Type

Total Promoters

Total Promoters that overlap LTRs

% of Total Promoters that overlap LTRs

Cell-line Specific Promoters

% Cell-line Specific Promoters

Cell-line Specific Promoters that overlap LTRs

% of Cell line Specific Promoters that overlap LTRs

Number of LTRs that overlaps cell-line specific Promoters

K562

Malignant

15,627

1,199

7.7%

1,599

10.2%

427

26.7%

622

HepG2

Malignant

15,993

1,165

7.3%

1,886

11.8%

303

16.1%

400

GM12878

Immortalized

15,279

989

6.5%

1,613

10.6%

153

9.5%

203

NHLF

Primary

14,888

546

3.7%

259

1.7%

15

5.8%

16

HMEC

Primary

13,711

535

3.9%

145

1.1%

9

6.2%

12

HSMM

Primary

14,335

537

3.7%

305

2.1%

23

7.5%

25

HUVEC

Primary

12,319

397

3.2%

102

0.8%

6

5.9%

7

NHEK

Primary

14,009

700

5.0%

219

1.6%

24

11.0%

29

H1-hESC

Embryonic Stem

12,477

568

4.6%

453

3.6%

217

47.9%

308