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Table 1 Dataset of known, candidates and mutated cancer genes

From: Integrated analysis of recurrent properties of cancer genes to identify novel drivers

Cancer type Known cancer genes Candidate cancer genes Rest of mutated genes Tumour samples References
Bladder 24 9 380 97 [8]
Breast 165 280 1,520 196 [2, 11, 40, 52]
Colorectal 42 124 654 11 [2]
Gastric 203 14 5,160 109 [16]
Glioblastoma 127 87 1,679 197 [5, 12, 39]
HNSCC 221 67 5,901 194 [15, 35]
Kidney 71 15 655 517 [7, 9, 55]
Leukaemia 58 169 877 393 [18, 41, 44, 46, 50, 51]
Liver 26 66 370 140 [45, 53]
Lung 218 143 1,012 324 [4, 11, 43, 49]
Lymphoma 46 47 574 133 [14, 47]
Medulloblastoma 16 1 194 88 [13]
Melanoma 96 159 2,845 16 [17, 48, 54]
Myelodysplasia 22 4 206 29 [57]
Myeloma 69 6 1,260 37 [6]
Oligodendroglioma 12 0 149 34 [38]
Ovarian 60 80 109 58 [11]
Pancreas 77 194 1,070 205 [10, 11, 42, 56]
Prostate 54 161 81 67 [11, 37]
Sarcoma 11 10 0 207 [36]
Total 444 608 9,629 3,052 NA
  1. Starting from 10,681 human genes with at least one cancer-specific non-synonymous mutation, three groups were identified: known cancer genes that are part of the cancer gene census [58]; candidate genes that are likely to play a role in cancer because they are recurrently mutated; and the rest of mutated genes that carry at least one non-synonymous mutation. The full description of mutated genes in each of the 39 sequencing screenings is reported in Additional file 2, Table S1. HNSCC; head and neck squamous cell carcinoma.