Table 2 Top five performing features for microdeletion and microinsertion discrimination.
From: DDIG-in: discriminating between disease-associated and neutral non-frameshifting micro-indels
Features | MCCa | AUCb | Precision | Recall |
|---|---|---|---|---|
Deletion | ||||
Disorder (Min, Ave, Max) | 0.558, 0.557, 0.551 | 0.824, 0.825, 0.818 | 74%, 74%, 73% | 85%, 85%, 84% |
ASAc (Min, Ave, Max) | 0.542, 0.47, 0.302 | 0.81, 0.781, 0.659 | 73%, 71%, 68% | 88%, 81%, 57% |
DNA conservation (Max, Ave, Min) | 0.468, 0.367, 0.144 | 0.781, 0.742, 0,561 | 68%, 72%, 66% | 79%, 71%, 23% |
Neffd (Min, Ave, Max) | 0.449, 0.439, 0.43 | 0.735, 0.749, 0.729 | 68%, 66%, 67% | 85%, 87%, 85% |
Probability of sheet (Max, Min Ave) | 0.32, 0.305, 0.284 | 0.678, 0.658, 0.632 | 69%, 69%, 64% | 60%, 53%, 51% |
Insertion | ||||
Disorder (Min, Max, Ave) | 0.556, 0.546, 0.545 | 0.813, 0.816, 0.80 | 78%, 80%, 79% | 75%, 74%, 75% |
ASAc (Min, Ave, Max) | 0.501, 0.454, 0.317 | 0.80, 0.78, 0.670 | 71%, 78%, 71% | 85%, 65%, 52% |
Neff d (Min, Ave, Max) | 0.467, 0.455, 0.438 | 0.751, 0.747, 0.742 | 68%, 68%, 67% | 86%, 85%, 84% |
DNA conservation (Max, Ave, Min) | 0.453, 0.422, 0.234 | 0.758, 0.752, 0.597 | 72%, 74%, 76% | 75%, 65%, 27% |
Transition probability of microinsertion to match (Min) | 0.372 | 0.708 | 72% | 62% |