Heatmap of relative expression of key miRNAs. Log2(normalized counts per million) are centered and scaled by row. For clarity, expression data from only the second replicate are shown. Sidebars show average log2 cpm across all 16 treatments and significant fold changes at each transition between stages of reprogramming as determined by edgeR. Dlk1-Dio3 miRNAs are shown in order from 5′ to 3′. EMT, epithelial-mesenchymal transition. See also Figure S3 in Additional file 1.