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Figure 8 | Genome Biology

Figure 8

From: Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation

Figure 8

Examples of co‐regulated protein complexes. (A) Eukaryotic initiation factor 3. (B) ATP synthase complex. (C) MCM complex. (D) Exosome. (E) TRiC/CCT complex according to DPiM. (F) TRiC/CCT complex extended for co‐regulated subunits (indicated by asterisks). (G) Prefoldin complex. The centers of the nodes indicate protein expression changes and the borders of the nodes mRNA expression changes. Blue represents downregulation, red represents upregulation and the color intensity is proportional to the level of regulation. Transcripts and proteins not quantified are shown in gray. Protein interactions are depicted as light green lines and their thickness is proportional to the interaction strength. DPiM, Drosophila protein interaction map; MCM, minichromosome maintenance complex; TRiC/CCT, TCP‐1 ring complex or chaperonin‐containing TCP‐1 complex.

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Genome Biology

ISSN: 1474-760X

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