Figure 6

Global protein interaction map integrated with mRNA and protein expression changes. Visualization of mRNA and protein expression changes for all Drosophila protein interaction map clusters [39] using Cytoscape. Clustered proteins tend to be co‐regulated. The centers of the nodes indicate protein expression changes and the borders of the nodes mRNA expression changes. Blue represents downregulation, red represents upregulation and the color intensity is proportional to the level of regulation. Transcripts and proteins not quantified are shown in gray. Protein interactions are depicted as light green lines and their thickness is proportional to the interaction strength. See Additional file 4 for details.