Figure 3From: Sequence signatures extracted from proximal promoters can be used to predict distal enhancersExperimental validation of liver enhancer predictions using the hydrodynamic tail vein enhancer assay. On each injection day, we also injected an empty pGL4.23[luc2] vector and a known liver enhancer of the ApoE gene as negative and positive controls, respectively. At least three mice were injected per construct. Statistical significance was tested using Student’s t-test followed by multiple testing adjustment with Benjamini-Hochberg’s method. The asterisks indicate statistical significance to control at adjusted P-value ≤0.05.Back to article page