Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3

Table 2 TCF7L2 binds to enhancer regions

Cell line	Percentage of TCF7L2 peaks at H3K4me1 sites	Percentage of TCF7L2 peaks at H3K27Ac sites	Percentage of TCF7L2 peaks at active enhancers (H3K4me1 and H3K27Ac)
HCT116	68	72	57
HepG2	84	59	56
PANC1	63	74	55
HeLa	72	58	53
MCF7	34	46	25

TCF7L2 peaks were overlapped with called peaks for H3K27Ac or H3K4me1 or both H3K27Ac and H3K4me1 in the same cell line. The percentage of TCF7L2 peaks in each category is indicated.

ISSN: 1474-760X