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Table 1 Pearson correlations between features and negative genetic interaction degree in S. pombe (pom) and S. cerevisiae (cer) are observed to be significant in many cases

From: Conserved rules govern genetic interaction degree across species

  Pearson's r P-value 95% CI
SM fitness defect    
   pom 0.48 9.90E-31 [0.41, 0.54]
   cer 0.75 0.00E+00 [0.77, 0.74]
Multifunctionality    
   pom 0.3 1.01E-12 [0.22, 0.37]
   cer 0.26 4.52E-53 [0.29, 0.23]
Conservation    
   pom 0.07 1.06E-01 [-0.01, 0.15]
   cer 0.16 7.11E-21 [0.19, 0.13]
Broad conservation    
   pom 0 9.30E-01 [-0.09, 0.08]
   cer 0.16 9.90E-19 [0.19, 0.12]
PPI degree    
   pom 0.2 5.84E-03 [0.06, 0.33]
   cer 0.15 1.49E-19 [0.19, 0.12]
Expression level    
   pom -0.05 2.42E-01 [-0.13, 0.03]
   cer 0.11 7.40E-10 [0.14, 0.08]
Disorder    
   pom 0.13 3.05E-03 [0.04, 0.21]
   cer 0.11 1.91E-10 [0.14, 0.08]
Codon Adaptation Index    
   pom -0.02 6.49E-01 [-0.1, 0.06]
   cer 0.09 1.91E-07 [0.12, 0.06]
Protein length    
   pom 0 9.18E-01 [-0.08, 0.09]
   cer 0.05 3.57E-03 [0.08, 0.02]
Co-expression degree    
   pom 0 9.38E-01 [-0.08, 0.09]
   cer 0.05 3.75E-03 [0.08, 0.02]
Number of domains    
   pom -0.01 7.37E-01 [-0.1, 0.07]
   cer 0.01 4.54E-01 [0.05, -0.02]
Number of unique domains    
   pom -0.02 6.86E-01 [-0.1, 0.07]
   cer 0.01 6.98E-01 [0.04, -0.03]
Nc    
   pom -0.01 7.56E-01 [-0.1, 0.07]
   cer -0.08 2.95E-06 [-0.05, -0.11]
dN/dS    
   pom -0.05 2.48E-01 [-0.14, 0.04]
   cer -0.11 1.58E-09 [-0.07, -0.14]
Copy number    
   pom -0.08 5.26E-02 [-0.17, 0]
   cer -0.12 1.01E-11 [-0.08, -0.15]
Expression variation    
   pom -0.15 4.11E-04 [-0.23, -0.07]
   cer -0.18 3.87E-27 [-0.15, -0.21]
  1. CI, confidence interval; PPI, protein-protein interaction; SM, single mutant