Skip to main content

Table 1 Overview of protein domains that are enriched among proteins not previously known to bind RNA

From: The greatest catch: big game fishing for mRNA-bound proteins

Putative non-classical RNA-binding domain

Identified in study led by:

Domain previously described to bind RNA

 

Hentze [2]

Landthaler [3]

 

AlbA-like DNA binding

 

✔

Yes

CBF

✔

 

No

DZF

 

✔

No

FAST and RAP

✔

✔*

No

HAT helix

 

✔

No

HMG box

✔¶

✔

Yes

MMR HSR1

✔

 

No

PAP associated

✔

✔*

No

polyK-patches

✔

 

No

SAP

✔

✔

Yes

SWAP/SURP

 

✔

Yes

WD40

✔

 

Yes

'Winged helix' DNA binding

 

✔

No

YGG boxes

✔

 

No

ZNF motif

   

   Subtype AKAP95

✔

✔*

No

   Subtype HC5HC2H

✔

 

No

  1. *Corrected P-value >0.05; ¶P-value >0.1.