The genomic landscape shaped by selection on transposable elements across 18 mouse strains

Table 1 Orientation bias values of TEVs or apparently fixed TEs in the mouse genome

	Sense	Antisense	Percentage sense	Chi-square test P-value
ERV TEV	2,042	4,176	32.8%	0.61
Apparently fixed ERV	61,857	128,263	32.5%
LINE TEV	3,803	5,336	41.6%	3. 5 × 10^-33
Apparently fixed LINE	81,655	148,497	35.5%
SINE TEV	4,192	5,528	43.1%	1.2 × 0^-4
Apparently fixed SINE	282,011	343,528	45.1%

For each TE superfamily the number of intronic variants within mouse genes with human orthologs was counted. B6⁺ TEVs and apparently fixed C57BL6/J TEs were counted as either sense or antisense with respect to the gene's transcriptional orientation. Significant differences between the orientation biases of apparently fixed and variant TEs were obtained using a chi-square test.

ISSN: 1474-760X