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Table 1 Comparison of performance of methods with respect to identifying the four inversions on Venter chromosome 17

From: An integrative probabilistic model for identification of structural variation in sequencing data

Method

Minimum number to detect 3

Minimum number to detect 4

High quality alignments

  

   Breakdancer

3

NA

   GASV

3

NA

   GASVPro-HQ

3

NA

   Hydra-HQ

4

NA

All alignments

  

   GASVPro

3

4

   Hydra

5

10

  1. GASVPro is the only method with perfect specificity and sensitivity, detecting all four inversions with no false positive predictions. NA, not applicable.