Figure 11From: Defining the molecular profile of planarian pluripotent stem cells using a combinatorial RNA-seq, RNA interference and irradiation approachRegulation of NBs relies heavily on PTGR mechanisms. (a-f) Smed-H2B(RNAi) IS versus irradiation IS plot of the transcripts compiled with KEGG (BRITE hierarchies) transcription factors (a, magenta), KEGG pathways 'RNA polymerase' and 'Basal transcription factors' (b, blue), KEGG pathway 'Spliceosome' (c, red), KEGG pathway 'RNA transport' (d, green), KEGG pathway 'mRNA surveillance' (e, yellow) and KEGG pathway 'RNA degradation' (f, cyan). Green horizontal lines represent the median Smed-H2B(RNAi) IS of each compilation. Several transcription factors are found in our list of NB-expressed transcripts, but they are not significantly enriched (a), and similarly, transcription machinery is not significantly enriched either (b). However, a strong enrichment is found for spliceosome components (c). Other RNA-associated processes, such as RNA transport (d), mRNA surveillance (e) and RNA degradation (f), are enriched as well with various significances.Back to article page