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Table 3 Proteins co-purified with candidate COX assembly factors

From: Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome coxidase

 

Purified

Tagged

COX7A2

COX17

C1orf31

C7orf44-TAP

-

+

+

PET100-TAP

+

+

-

PET117-TAP

-

+

-

C12orf62-TAP

-

+

-

AURKAIP1-TAP

-

-

-

  1. COX-associated proteins co-purified with the predicted COX assembly factors but not with control proteins. COX7A2 is COX subunit VIIa, COX17 is a known COX assembly factor and C1orf31 is a predicted assembly factor. In all induced samples the bait protein was identified (Materials and methods).
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Genome Biology

ISSN: 1474-760X

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