Figure 3
From: Whole-genome reconstruction and mutational signatures in gastric cancer
Genome-wide and exome-wide mutational fingerprint. (a) Frequency of various classes of somatic SNVs genome-wide. (b) Frequency of somatic SNVs exome-wide. (c) Mutational bias as a function of infection status using data from 34 exomes (bias for SNV class i was computed as (si - gi)/gi, where si and gi are the somatic and germline SNV frequencies). Note that nearly identical results were obtained when MSI tumors were excluded from the analysis (*P-value < 0.1; **P-values < 0.01, respectively). (d) Size-distribution of germline and somatic indels genome-wide.