Comparison of the probe designs of the exome capture kits against CCDS exon annotations. (a, b) Given are the numbers of CCDS exon regions, common target regions outside CCDS annotations and the regions covered individually by the Agilent SureSelect and NimbleGen SeqCap sequence capture kits (a) and the Agilent SureSelect 50 Mb and NimbleGen SeqCap v2.0 sequence capture kits (b). Regions of interest are defined as merged genomic positions regardless of their strandedness, which overlap with the kit in question. Sizes of the spheres are proportional to the number of targeted regions in the kit. Total numbers of targeted regions are given under the name of each sphere.