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Table 7 Comparison of the CpG transition rate between the X chromosome and the 22 autosomes

From: Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content

  CpG specific transition rate CpG transition rate
Levels of the one-way ANOVA Estimate P-value Estimate P-value
Intercept -0.0708 1.04e-03** -0.1730 6.82e-15***
Chromosome 1 0.0638 1.58e-02* 0.1531 1.83e-08***
Chromosome 2 0.0565 3.32e-02* 0.1567 9.46e-09***
Chromosome 3 0.0870 1.21e-03** 0.1809 5.97e-11***
Chromosome 4 0.0644 2.46e-02* 0.1759 2.37e-09***
Chromosome 5 0.0437 1.20e-01 0.1374 2.03e-06***
Chromosome 6 0.0579 4.94e-02* 0.1666 3.86e-08***
Chromosome 7 0.0330 2.97e-01 0.1293 6.84e-05***
Chromosome 8 -0.0036 9.08e-01 0.1382 1.53e-05***
Chromosome 9 0.0942 2.71e-03** 0.1890 4.94e-09***
Chromosome 10 0.0871 2.95e-03** 0.1864 6.22e-10***
Chromosome 11 0.0988 1.44e-03** 0.1911 2.09e-09***
Chromosome 12 0.0555 6.11e-02 0.1345 1.03e-05***
Chromosome 13 0.0625 8.53e-02 0.1501 5.88e-05***
Chromosome 14 0.0005 8.88e-01 0.0900 9.89e-03**
Chromosome 15 0.0333 9.87e-01 0.1376 2.74e-05***
Chromosome 16 0.0630 1.13e-01 0.1707 2.92e-05***
Chromosome 17 -0.0011 9.74e-01 0.1144 1.33e-03**
Chromosome 18 0.0862 1.92e-02* 0.1901 5.02e-07***
Chromosome 19 -0.0118 8.68e-01 0.1157 1.15e-01
Chromosome 20 -0.0077 8.46e-01 0.0756 6.28e-02
Chromosome 21 0.1033 5.49e-02 0.2319 2.76e-05***
Chromosome 22 0.0288 6.00e-01 0.1228 2.99e-02*
  1. CpG-specific transition rate is corrected for among-chromosomes variation in divergence, GC content, DNA methylation and transcription level; CpG transition rate is only corrected for variation in GC content, DNA methylation and transcription level among chromosomes. Estimates and P-values of a one-way ANOVA are listed, where the contrasts are based on the X chromosome. P-values are marked with asterisks to highlight their significance level, where single, double and triple asterisks indicate P-values below a threshold of 0.05, 0.01 and 0.001, respectively.