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Table 2 Summary of parameter estimates and significance levels of the multivariate generalized linear regression analysis for CpG transition rate

From: Substitution rate variation at human CpG sites correlates with non-CpG divergence, methylation level and GC content

  Dataset A Dataset B Dataset C
  Estimate -log10(p) Estimate -log10(p) Estimate -log10(p)
Divergence 0.1832 > 15.70 0.1574 > 15.70 0.1722 > 15.70
Methylation level 0.0385 9.50 0.1047 > 15.70 0.3454 > 15.70
GC content -0.1036 > 15.70 -0.1382 > 15.70 -0.1849 > 15.70
Transcription level -0.0145 1.95 -0.0094 3.01 -0.0114 1.46
Female recombination rate 0.0031 0.22 0 0 0.0158 2.29
Male recombination rate -0.0054 0.43 -0.0084 2.29 -0.0167 2.42
Explained deviance 1,243 5,310 8,038
Residual deviance 5,894 10,496 3,451
na 13,038 21,636 3,871
AICb 37,300 78,030 17,172
  1. Dataset A contains no CpG islands (CGIs) or DNase I hypersensitive sites (DHSs)), dataset B contains DHSs but no CGIs, and dataset C contains both CGIs and DHSs. aSample size. bAkaike Information Criterion.