Table 1 Nominally significant (P < 0.05) gene expression correlations with cellular sensitivity to chemotherapeutic agents
From: Copy number polymorphisms and anticancer pharmacogenomics
Gene | Drug | P-value | Chromosome |
|---|---|---|---|
AKT1S1 | Carboplatin | 0.04497 | 19 |
AKT1S1 | Daunorubicin | 0.01149 | 19 |
AKT1S1 | Etoposide | 0.00610 | 19 |
ALKBH8 | Daunorubicin | 0.01151 | 11 |
AMY1A | Etoposide | 0.03933 | 1 |
AMY2A | Etoposide | 0.03933 | 1 |
ANKLE1 | Carboplatin | 0.03017 | 19 |
ANKLE1 | Daunorubicin | 0.01706 | 19 |
ANKRD36B | Daunorubicin | 0.02380 | 2 |
BCLAF1 | Daunorubicin | 0.01498 | 6 |
C13orf3 | Carboplatin | 0.00830 | 13 |
C13orf3 | Cisplatin | 0.01980 | 13 |
C13orf3 | Daunorubicin | 0.00572 | 13 |
C18orf1 | Cisplatin | 0.00398 | 18 |
CAB39L | Etoposide | 0.04179 | 13 |
DIS3L2 | Daunorubicin | 0.03077 | 2 |
DNAJC5 | Carboplatin | 0.00166 | 20 |
DNAJC5 | Cisplatin | 0.04058 | 20 |
FBRS | Carboplatin | 0.00661 | 16 |
FGFR4 | Carboplatin | 0.00556 | 5 |
FKBP14 | Carboplatin | 0.03912 | 7 |
FLI1 | Carboplatin | 0.04735 | 11 |
FLI1 | Daunorubicin | 0.00314 | 11 |
FLI1 | Etoposide | 0.04230 | 11 |
GALNT1 | Daunorubicin | 0.00065 | 18 |
GPR107 | Etoposide | 0.00674 | 9 |
GPR137 | Carboplatin | 0.00616 | 11 |
GPR137 | Cisplatin | 0.00828 | 11 |
GPR137 | Etoposide | 0.01493 | 11 |
GPR144 | Etoposide | 0.04526 | 9 |
GSPT1 | Carboplatin | 0.04002 | 16 |
GSPT1 | Cisplatin | 0.01429 | 16 |
HLA-DQA1 | Daunorubicin | 0.00946 | 6 |
HLA-DQA1 | Etoposide | 0.00022 | 6 |
IGLV3-21 | Carboplatin | 0.04800 | 22 |
MOXD1 | Carboplatin | 0.00002 | 6 |
MOXD1 | Cisplatin | 0.00002 | 6 |
MOXD1 | Daunorubicin | 0.03454 | 6 |
MOXD1 | Etoposide | 0.00007 | 6 |
MTA1 | Etoposide | 0.01401 | 14 |
NCOA1 | Daunorubicin | 0.04278 | 2 |
NEK6 | Carboplatin | 0.04050 | 9 |
NUB1 | Etoposide | 0.02671 | 7 |
PPP1R3B | Cisplatin | 0.03039 | 8 |
PTP4A2 | Carboplatin | 0.01930 | 1 |
PTP4A2 | Cisplatin | 0.01182 | 1 |
PTP4A2 | Etoposide | 0.03348 | 1 |
RCC1 | Carboplatin | 0.01252 | 1 |
RCC1 | Cisplatin | 0.01722 | 1 |
RCC1 | Daunorubicin | 0.00002 | 1 |
RCC1 | Etoposide | 0.01358 | 1 |
RNF103 | Daunorubicin | 0.02655 | 2 |
RPN2 | Daunorubicin | 0.01206 | 20 |
SLC10A7 | Daunorubicin | 0.00481 | 4 |
SLC4A8 | Cisplatin | 0.02189 | 12 |
SLC4A8 | Etoposide | 0.00248 | 12 |
SMPD4 | Daunorubicin | 0.02446 | 2 |
SNRK | Carboplatin | 0.00396 | 3 |
SNRK | Cisplatin | 0.00479 | 3 |
SNRK | Daunorubicin | 0.02429 | 3 |
SULF2 | Carboplatin | 0.00002 | 20 |
SULF2 | Cisplatin | 0.00053 | 20 |
SULF2 | Daunorubicin | 0.00014 | 20 |
SULF2 | Etoposide | 0.00000 | 20 |
TBC1D22A | Cisplatin | 0.03807 | 22 |
TBL1XR1 | Carboplatin | 0.04028 | 3 |
TFDP1 | Cisplatin | 0.04967 | 13 |
TNK2 | Carboplatin | 0.01901 | 3 |
TNK2 | Daunorubicin | 0.00431 | 3 |
TNK2 | Etoposide | 0.01159 | 3 |
TYRO3 | Etoposide | 0.02840 | 15 |
UPK3B | Cisplatin | 0.02839 | 7 |
WDR90 | Daunorubicin | 0.02575 | 16 |
WDR90 | Etoposide | 0.00111 | 16 |
ZDHHC4 | Daunorubicin | 0.02463 | 7 |
ZFAND2A | Daunorubicin | 0.00227 | 7 |
ZFAND2A | Etoposide | 0.03567 | 7 |
ZNF277 | Etoposide | 0.04521 | 7 |
ZNF331 | Carboplatin | 0.02122 | 19 |
ZNF664 | Carboplatin | 0.04722 | 12 |