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Table 5 Concentrations of CMP, AMP, GMP, XMP, and TMP

From: Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidisand human cells

 

Control

0.16 μM IQ-143

1.25 μM IQ-143

 

Mean (μg/ml)

SD

Mean (μg/ml)

SD

% of control

Mean (μg/ml)

SD

% of control

CMP

21.03

0.96

24.41*

0.24

116.07

3.86**

0.19

18.35

TMP

1.61

0.12

1.67

0.11

103.76

8.81*

0.24

547.20

AMP

0.42

0.06

0.12*

0.02

28.57

20.37**

0.80

4850.00

GMP

1.51

0.05

1.44**

0.05

95.36

3.66*

0.21

242.38

XMP

2.62

0.20

3.96**

0.16

151.15

3.44**

0.11

131.30

  1. Direct measurement of CMP, AMP, GMP, XMP, and TMP concentrations in S. aureus (in μg/ml and in percentage of control value depending on the applied IQ-143 concentration). Statistically significant differences are indicated (*P < 0.05,**P < 0.01). SD, standard deviation.
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Genome Biology

ISSN: 1474-760X

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