| |
Control
|
0.16 μM IQ-143
|
1.25 μM IQ-143
|
|---|
| |
Mean (μg/ml)
|
SD
|
Mean (μg/ml)
|
SD
|
% of control
|
Mean (μg/ml)
|
SD
|
% of control
|
|---|
|
CMP
|
21.03
|
0.96
|
24.41*
|
0.24
|
116.07
|
3.86**
|
0.19
|
18.35
|
|
TMP
|
1.61
|
0.12
|
1.67
|
0.11
|
103.76
|
8.81*
|
0.24
|
547.20
|
|
AMP
|
0.42
|
0.06
|
0.12*
|
0.02
|
28.57
|
20.37**
|
0.80
|
4850.00
|
|
GMP
|
1.51
|
0.05
|
1.44**
|
0.05
|
95.36
|
3.66*
|
0.21
|
242.38
|
|
XMP
|
2.62
|
0.20
|
3.96**
|
0.16
|
151.15
|
3.44**
|
0.11
|
131.30
|
- Direct measurement of CMP, AMP, GMP, XMP, and TMP concentrations in S. aureus (in μg/ml and in percentage of control value depending on the applied IQ-143 concentration). Statistically significant differences are indicated (*P < 0.05,**P < 0.01). SD, standard deviation.
