Figure 1

Protein abundance versus relative location and strength of the bottleneck in the GFP library. (a) All the genes in the GFP library. The x-axis is the relative location of the bottleneck in every gene; the y-axis is the per-cell protein abundance. The color of each dot is the relative strength of the bottleneck in every gene. Eighty-six of the genes are located between the two black lines that correspond to relatively early bottlenecks - that is, relative location between 0.16 and 0.28. (b) The correlation between the bottleneck relative strength and per-cell protein abundance for all the genes in the GFP library. The 86 genes that have a relative location between 0.16 and 0.28 are plotted as red squares, and the rest of the genes are plotted as grey circles.