Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer

Table 1 Patient overview and tumor status

Patient ID	Gender	Type	Primary tumor grade	Metastasis resection^a	Treatment^b
Patient 1	Female	Adenocarcinoma	Moderately differentiated	3 months	No treatment
Patient 2	Male	Adenocarcinoma	Moderately differentiated	20 months	No treatment
Patient 3	Male	Adenocarcinoma	Poorly differentiated	10 months	XELOX^c and Bevacizumab
Patient 4	Female	Adenocarcinoma	Well differentiated	9 months	5FU, leucovorin, oxaliplatin, bevacizumab

^aTime between primary resection and metastasis resection. ^bTreatment after primary tumor resection. ^cCapecitabine and oxaliplatin. 5FU, fluorouracil.