Dynamics of genomes during animal evolution. The functional contents of inferred ancestral genomes from the LECA to hominids (humans and great apes) are shown. (a) GO categories involved in various aspects of regulation. (b) GO categories involved in various aspects of metabolism (for detailed results see Additional files 5 and 6). Divergence time estimates are based on the fossil record and thus are minimum time constrains [39, 68, 69]. Geological periods are indicated on both panels ('Ed' stands for Ediacaran period and 'Cz' for Cenozoic era).