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Open Access

Transcriptomics in a high throughput world

  • Chad Nusbaum1
Genome Biology201011(Suppl 1):I12

Published: 11 October 2010


Sequencing DatacDNA LibraryCurrent WorkHigh ThroughputData Yield

Sequencing-based approaches are transforming our ability to investigate, interpret and define transcriptomes, which comprise the expressed elements in genomes. This is driven by innovations in all steps in the process, including sample preparation, cDNA library construction, increases in sequencing data yield and development of new computational approaches. I will describe the state of the art in the field as well as new approaches and results from current work in transcriptome analysis at the Broad Institute.

Authors’ Affiliations

Genome Sequencing and Analysis Program, Broad Institute, Cambridge, USA


© Nusbaum; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.