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  • Invited speaker presentation
  • Open Access

Transcriptomics in a high throughput world

  • 1
Genome Biology201011 (Suppl 1) :I12

  • Published:


  • Sequencing Data
  • cDNA Library
  • Current Work
  • High Throughput
  • Data Yield

Sequencing-based approaches are transforming our ability to investigate, interpret and define transcriptomes, which comprise the expressed elements in genomes. This is driven by innovations in all steps in the process, including sample preparation, cDNA library construction, increases in sequencing data yield and development of new computational approaches. I will describe the state of the art in the field as well as new approaches and results from current work in transcriptome analysis at the Broad Institute.

Authors’ Affiliations

Genome Sequencing and Analysis Program, Broad Institute, Cambridge, MA 02141, USA


© Nusbaum; licensee BioMed Central Ltd. 2010

This article is published under license to BioMed Central Ltd.