Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates

Table 1 Strain virulence in the mouse infection model (BALB/c)

Strain	Inoculum (cfu)	Mortality 4 days post infection	Mortality 13 days post infection
PBS	0	0/6	0/6
BpK96243	9	0/6	0/6
	118	0/6	4/6 (66.7%)
	380	0/6	4/6 (66.7%)
	1180	0/6	5/6 (83%)
	3600	1/6 (16.7%)	6/6 (100%)
Bp22	6	0/6	2/6 (33%)
	19	0/6	5/6 (83%)
	58	0/6	5/6 (83%)
	175	1/6 (16.7%)	6/6 (100%)
	525	2/6 (33%)	6/6 (100%)
BtE264	1000	0/6	0/6
	10⁴	0/6	0/6
	10⁵	0/6	0/6
	10⁶	0/6	0/6
	10⁷	1/6 (16.7%)	1/6 (16.7%)
BtE555	1,000	0/6	0/6
	10⁴	0/6	0/6
	10⁵	0/6	0/6
	10⁶	0/6	0/6
	10⁷	4/6 (66.7%)	4/6 (66.7)

Infection assays in BALB/c mice. Mice were monitored for up to 13 days post-infection with different starting amounts of bacteria (cfu column). Note the differences in cfu between Bp and Bt strains (starting cfu 6 to 9 versus 1,000). PBS, phosphate-buffered saline.

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