Table 1 Genetic loci involved in sex determination in vertebrates
From: Are homologies in vertebrate sex determination due to shared ancestry or to limited options?
Locus | Gene name | Type of protein product |
|---|---|---|
SRY | Sex-determining region on the Y chromosome | HMG-box transcription factor |
SOX3 | SRY-like, HMG-box-containing gene family, member 3 | HMG-box transcription factor |
SOX9 | SRY-like, HMG-box-containing gene family, member 9 | HMG-box transcription factor |
SF1 | Steroidogenic factor 1 | Transcription factor of the steroid receptor family |
FGF9 | Fibroblast growth factor 9. | Secreted intercellular signal |
WNT4 | Wingless-type MMTV integration site family, member 4 | Secreted intercellular signal |
RSPO1 | R-spondin-1 | Secreted intercellular signal |
DMRT1 | Doublesex and mab-3 related transcription factor 1 | Transcription factor |
DMY | DMRT1 homolog on the Y in Oryzias latipes | Transcription factor |
DM-W | DMRT1 homolog on the W in Xenopus laevis | Transcription factor |
DGCR8 | DiGeorge syndrome critical region, gene 8 | microRNA biogenesis protein |
RBMY | RNA-binding motif protein, Y-linked | RNA binding protein |
TSPY | Testis-specific protein, Y-linked | Growth promoting factor and candidate gonadoblastoma gene. |