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Table 3 MicroRNA overexpression motif predictions

From: Evidence-ranked motif identification

  mRNA_32 hr Protein
  Seed motif Score ERMIT Score Seed motif Score ERMIT Score
let-7b CTACCTc 5.4 GSCCCCS 15.2 CTACCTc 9.1 MTACCTcw 9.7
miR-1 ACATTCc 13.8 RCATTCc 14.5 ACATTCc 8.5 wnRCATTCc 9.9
miR-16 gCTGCTA 7.4 wwgCTGCT 10.2 gCTGCTA 10.3 tgCKGCTR 11.6
miR-155 AGCATTa 12.6 WGCRTTa 13.6 AGCATTa 13.4 GCATTaw 15.2
miR-30a gTTTACA 10.0 ygTTTACR 10.9 gTTTACA 7.5 wgTTTACAw 8.5
  1. The letters in bold correspond to the canonical 6-mer microRNA seed (that is, the complementary sequence to positions 2 through 7). For each microRNA we report the best of four canonical 6- to 8-mer seed match scores based on the ERMIT objective function, and the corresponding motif prediction resulting from the motif search (data from [44]).