Figure 3

Expressed fusion genes found in tumor PD3680a. (a) Schematic representation of the fusion of genes Tpd52l1 and Rnf217 by tandem duplication. (b) RT-PCR product of RNA between exon 2 of Tpd52l1 and exon 2 of Rnf217. Sequence trace of the RT-PCR product confirming the fusion at the RNA level. A schematic representation of the putative fusion gene product. IBR-ZNF, in between ring fingers-zinc finger domain PF01485; TM, transmembrane domain - predicted by TMHMM. (c) Schematic representation of the fusion of genes Aldh8a1 and 6330407J23Rik by deletion. (d) RT-PCR product of RNA between exon 6 of Aldh8a1 and exon 5 of 6330407J23Rik. Sequence trace of the RT-PCR product confirming the fusion at the RNA level. A schematic representation of the putative fusion gene product. Retinoic acid DH, aldehyde dehydrogenase PF00171; TM, transmembrane domain - predicted by TMHMM.