Heatmap showing the conservation of individual metabolic pathways. Each row indicates an individual metabolic pathway grouped by their superclass membership (defined by KEGG). Each column indicates specific taxonomic divisions (see Materials and methods; Table 1). Colored tiles indicate the level of conservation (percentage of enzymes detected) of each pathway within each taxonomic group (see inset color key top left). For example, many Glycan metabolic pathways are poorly conserved with the exception of several groups of metazoans.