Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana

Table 2 Co-localization of H3K4me and H3K27me3 in the same genome regions

	Total regions	Overlap with H3K27me3	%	Random overlapping*	Enriched for H3K27me3?	Depleted of H3K27me3?
H3K4me1	15,475	178	1.15	4.78%	No (P = 1)	Yes (P < 10^-10)
H3K4me2	12,781	881	6.89	6.09%	Yes (P = 1.0 × 10^-4)	No (P = 1)
H3K4me3	15,894	572	3.60	7.12%	No (P = 1)	Yes (P < 10^-10)

*For each H3K27me3-containing genomic region, a genomic region of the same length was randomly selected within its 10-kb upstream or downstream flanking regions. The set of random control regions thus resemble the H3K27me3 in both length and chromosomal distributions. The overlapping frequencies of the random control regions with H3K4me-containing regions were then determined.

ISSN: 1474-760X