Density of TCs in target genes compared to bystander genes, other CpG genes and other TFs. Average TC density calculated in sliding windows of 250 bp over a 4,000 bp region for each gene set. Average TC densities with 90% confidence intervals of bystanders, other CpG island genes, and other TFs are compared with target genes. (a) TC frequencies of targets and bystanders. (b) TC frequencies of targets and other CpG genes. (c) TC frequencies of targets and other TFs.