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Table 5 DNA-binding TF gene classification counts

From: TFCat: the curated catalog of mouse and human transcription factors

Protein group Protein group description Protein family Protein family description Gene count Predicted occurrences
1.1 Helix-turn-helix group 2 Homeodomain family 131 160
1.1 Helix-turn-helix group 100 Myb domain family 7 16
1.1 Helix-turn-helix group 109 Arid domain family 5 5
1.1 Helix-turn-helix group 999 No family level classification 2 2
1.2 Winged helix-turn-helix 13 Interferon regulatory factor 7 7
1.2 Winged helix-turn-helix 15 Transcription factor family 10 11
1.2 Winged helix-turn-helix 16 Ets domain family 23 23
1.2 Winged helix-turn-helix 101 GTF2I domain family 2 12
1.2 Winged helix-turn-helix 102 Forkhead domain family 26 26
1.2 Winged helix-turn-helix 103 RFX domain family 4 4
1.2 Winged helix-turn-helix 111 Slide domain family 1 1
2.1 Zinc-coordinating group 17 Beta-beta-alpha-zinc finger family 79 450
2.1 Zinc-coordinating group 18 Hormone-nuclear receptor family 43 43
2.1 Zinc-coordinating group 19 Loop-sheet-helix family 1 1
2.1 Zinc-coordinating group 104 GATA domain family 7 12
2.1 Zinc-coordinating group 105 Glial cells missing (GCM) domain family 2 2
2.1 Zinc-coordinating group 106 MH1 domain family 3 3
2.1 Zinc-coordinating group 114 Non methyl-CpG-binding CXXC domain 2 4
2.1 Zinc-coordinating group 999 No family level classification 2 2
3 Zipper-type group 21 Leucine zipper family 41 64
3 Zipper-type group 22 Helix-loop-helix family 71 71
4 Other alpha-helix group 28 High mobility group (Box) family 24 28
4 Other alpha-helix group 29 MADS box family 4 4
4 Other alpha-helix group 107 Sand domain family 3 3
4 Other alpha-helix group 115 NF-Y CCAAT-binding protein family 2 2
5 Beta-sheet group 30 TATA box-binding family 1 2
6 Beta-hairpin-ribbon group 34 Transcription factor T-domain 11 11
6 Beta-hairpin-ribbon group 108 Methyl-CpG-binding domain, MBD family 2 2
7 Other 37 Rel homology region family 10 10
7 Other 38 Stat protein family 6 6
7 Other 110 Runt domain family 3 3
7 Other 112 Beta_Trefoil-like domain family 2 2
7 Other 113 DNA-binding LAG-1-like domain family 2 2
8 Enzyme group 47 DNA polymerase-beta family 1 7
999 Unclassified structure 901 CP2 transcription factor domain family 3 3
999 Unclassified structure 902 AF-4 protein family 1 1
999 Unclassified structure 903 DNA binding homeobox and different transcription factors (DDT) domain family 1 1
999 Unclassified structure 904 AT-hook domain family 3 6
999 Unclassified structure 905 Nuclear factor I - CCAAT-binding transcription factor (NFI-CTF) family 3 3