Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq

Table 3 Comparison of ChIP-seq data with genome-wide association studies for identification of functional SNPs

Chr.	Position	SNP	Nearest/affected gene	Factor	Trait	Study
1	109,619,113	rs12740374	CELSR2, PSRC1, SORT1	FOXA1	LDL*/Dyslipidemia	Kathiresan et al.
10	101,851,425	rs11597390	CPN1	FOXA1, FOXA3	Plasma levels of liver enzymes (ALT^†)	Yuan et al.
1	109,620,053	rs646776	CELSR2-PSRC1-SORT1	H3K4me3	TC^‡/LDL	Aulchenko et al., Sabatti et al.
2	43,918,594	rs6756629	ABCG5	H3K4me3	TC/LDL	Aulchenko et al.
11	47,226,831	rs2167079	NR1H3	H3K4me3	HDL^§	Sabatti et al.
11	61,353,788	rs174570	FADS2/3	H3K4me3	TC/LDL	Aulchenko et al.
19	11,063,306	rs6511720	LDLR	H3K4me3	LDL/Dyslipidemia	Kathiresan et al.
19	50,087,106	rs157580	TOMM40-APOE, APO cluster	H3K4me3	TC/TG/LDL	Aulchenko et al., Sabatti et al.
19	50,087,459	rs2075650	TOMM40-APOE	H3K4me3	TC/LDL	Aulchenko et al.
22	23,320,213	rs4820599	GGT1	H3K4me3	Plasma levels of liver enzymes (GGT^¥)	Yuan et al

*LDL, low density lipoproteins. ^†ALT, alanine-aminotransferase. ^‡TC, total cholestrol. ^§HDL, high density lipoproteins. TG, triglycerides. ^¥GGT, gamma-glutamyl transferase.

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