H3K4me3 signals around 2,303 FOXA1-2-3 regions. (a) Enrichment of H3K4me3 in a window surrounding the center of FOXA1-2-3 regions. The regions were grouped into four clusters (I to IV) by their H3K4me3 patterns. The enrichment scale is from high (yellow) to low (blue), and the red vertical line represents the FOXA1-2-3 centers. Negative x-coordinates are upstream of the centers and positive are downstream. (b) Average H3K4me3 signal footprints for the four clusters in (a). (c) Average H3K4me3 signal footprints for regions with a TSS within 5 kb independent of direction (green) and regions lacking a TSS within this distance (purple).