Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophilacells

Table 2 Summary of Gene Ontology overrepresentation analysis of genes regulated by the wingless pathway

GO term category	Transcription (45)	AS (32)	AS only (38)
Signal transduction, lipid metabolism (for example, phospholipid metabolism)	14 (31%)	8 (25%)	5 (13%)
Learning, memory, behavior, olfaction	5 (11%)	7 (22%)	3 (8%)
Developmental decisions	10 (22%)	5 (16%)	11 (29%)
Cell death	3 (7%)	2 (6%)	2 (5%)
Carbohydrate, amino acid and intermediate metabolism	0	1 (3%)	2 (5%)
Immune response	0	0	0
RNA metabolism	0	0	0
Microtubule organization	0	0	0

GO overrepresentation analysis of the function (biological process) of genes regulated transcriptionally and at the level of alternative splicing by activation of the wingless pathway. GO terms were grouped in broad functional categories and the number of enriched GO terms in each category is indicated. Also indicated is the percentage that each number of enriched GO terms represents from the total number of enriched terms (indicated at the top) for the classes of genes showing transcriptional changes, alternative splicing (AS) changes or alternative splicing without transcriptional changes (AS only). Only GO term categories with a p-value < 0.05 are represented.

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