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Table 6 The area under the precision versus recall curve for different classifiers

From: Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiaegene function

GO branch GO specificity RF FL1* FL2* FL3* Funckenstein (RF + FL1) Funckenstein (RF + FL2) Funckenstein (RF + FL3)
BP 3 to 10 0.215 0.111 0.173 0.245 0.225 0.286 0.286
  11 to 30 0.306 0.197 0.296 0.359 0.331 0.422 0.441
  31 to 100 0.349 0.117 0.329 0.33 0.36 0.454 0.441
  101 to 300 0.394 0.169 0.373 0.394 0.405 0.492 0.491
MF 3 to 10 0.44 0.188 0.134 0.309 0.445 0.489 0.463
  11 to 30 0.557 0.296 0.216 0.383 0.558 0.599 0.565
  31 to 100 0.596 0.29 0.232 0.393 0.597 0.632 0.61
  101 to 300 0.75 0.55 0.24 0.595 0.753 0.77 0.762
CC 3 to 10 0.368 0.242 0.546 0.571 0.413 0.597 0.596
  11 to 30 0.377 0.261 0.441 0.465 0.417 0.523 0.524
  31 to 100 0.489 0.249 0.44 0.496 0.508 0.578 0.586
  101 to 300 0.524 0.271 0.391 0.468 0.537 0.591 0.595
  1. *FL1, FL classifier based on shared gene characteristics in Table 3; FL2, FL classifier based on direct gene-gene relationships in Table 4; FL3, FL classifier based on both relationship types. Entries in bold are the best Funckenstein classifier; entries in italics are the best individual classifier. BP, biological process; CC, cellular component; FL, functional linkage; GO, Gene Ontology; MF, molecular function; RF, random forest.