Sample*
|
CLL cells (%)†
|
Genomic region
|
Hemizygous loss by FISH (%)
|
Hemizygous loss by segmentation (%)‡
|
---|
8
|
87
|
17p13.3-p11.1
|
73
|
77
|
9
|
90
|
11q22.1-q23.3
|
56
|
58
|
10
|
86
|
17p13.3-p11.2
|
90
|
94
|
- *Data set 4. mBAF cut-off for each sample based on the maximum theoretical value for copy neutral LOH for the respective tumor content. †Percent CLL cells (CD5+/CD23+) were estimated by flow cytometry. ‡The average segmented value for the region was used.